65. Enantioselective Total Synthesis of (–)-TAN-67
Moursy, A.; Khamrai, J.; Obakpolor, O.; Altman, R. A.*
Manuscript Submitted.
63. Salicylate Protecting Group Strategies
Zhao, A.; Trombley, T. A.; Junaid, A.; Altman, R. A.*
Manuscript Submitted
62. The Effect of N-Alkyl Azole Difluorination on Molecular Properties Relevant for Lead Optimization: A Comparative Study
Herrick, R. M.; Green, S. A.; Rich, S.; Grandner, J. N.; Huard, K.;* Altman, R. A.*
61. On the Metabolic Stability of Fluorinated Small Molecules: A Physical Organic Chemistry Perspective
Bhattarai, P. B.; Trombley, T. A.; Altman, R. A.*
58. Unified Enantioselective Synthesis of 5-Phenylmorphans and cis-Octahydroisoquinolines
Mahgoub, A.; Khamrai, J.; Festus, O.; Altman, R. A.*
56. Discovery of RGS2-FBXO44 interaction inhibitors using a cell-based NanoBit assay
Aryal, S.; Wong, C. S. Y.; McNabb, H. J.; Junaid, A.; Altman, R. A.; Sjögren, B.*
Mol. Pharmacol. 2025, 107, 100030.
53. A Phenotypic High-Throughput Screen Identifies Small Molecule Modulators of Endogenous RGS10 in BV-2 Cells
Talele, S.; Gonzalez, S.; Trudeau, J.; Junaid, A.; Loy, C.; Altman, R. A.; Sjogren, J. B.*
52. α-Amino-β-Carboxymuconate-ε-Semialdehyde Decarboxylase Catalyzes Enol/Keto Tautomerization of Oxaloacetate
Yang, Y.; Davis, I.; Altman, R. A.; Liu, A.*
44. Fluoroalkylation of Dextromethorphan Improves CNS Exposure and Metabolic Stability
Sorrentino, J. P.; Altman, R. A.*
43. Modulating β-Arrestin-2 Recruitment at the δ- and μ-Opioid Receptors
Sharma K. S.; Cassell, R. J.; Meqbil, Y. J.; Su, H.; Blaine, A. T.; Cummins, B. R.; Mores, K. L.; Johnson, D.; van Rijn, R. M.;* Altman, R. A.*
40. Diflunisal Derivatives as Modulators of ACMS Decarboxylase Targeting the Tryptophan-Kynurenine Pathway
Yang, Y.; Borel, T.; de Azambuja, F.; Johnson, D.; Sorrentino, J. P.; Udokwu, C.; Davis, I.; Liu, A.;* Altman, R. A.*
37. Late-Stage Conversion of a Metabolically Labile Aryl Methyl Ether-Containing Natural Product to Fluoroalkyl Analogues
Sorrentino, J. S.; Ambler, B. R.; Altman, R. A.*
34. The Meta-Position of Phe4 in Leu-enkephalin Regulates Potency, Selectivity, Functional Activity, and Signaling Bias at the Delta and Mu Opioid Receptors
Cassell, R. J.; Sharma K. S.; Su, H.; Cummins, B. R.; Cui, H.; Mores, K. L.; Blaine, A. T.; Altman, R. A.;* van Rijn, R. M.*
29. Synthesis of Leu-Enkephalin Peptidomimetics Containing Trifluromethylalkenes as Amide Isopolar Mimics
Eeda, V.; Selvaraju, M.; Altman, R. A.*
28. Tyr1-ψ[(Z)CF═CH]-Gly2 Fluorinated Peptidomimetic Improves Distribution and Metabolism Properties of Leu-Enkephalin
Altman, R. A.*; Sharma, K. K.; Rajewski, L. G.; Toren, P. C.; Baltezor, M. J.; Pal, M.; Karad, S. N.
27. Stepwise O-Atom Transfer in Heme-based Tryptophan Dioxygenase: The Role of Substrate Ammonium in the Epoxide Ring Opening
Shin, I.; Ambler, B. R.; Wherritt, D.; Griffith, W.; Maldonado, A.; Altman, R. A.;* Liu, A.*
24. Synthesis and Opioid Activity of Tyr1–ψ[(Z)CF=CH]–Gly2 and Tyr1–ψ[(S)/(R)-CF3CH–NH]–Gly2 Leu-enkephalin Fluorinated Peptidomimetics
Karad, S. N.; Pal, M.; Crowley, R. S.; Prisinzano, T. E.; Altman, R. A.*