62. The Effect of N-Alkyl Azole Difluorination on Molecular Properties Relevant for Lead Optimization: A Comparative Study
Herrick, R. M.; Green, S. A.; Rich, S.; Grandner, J. N.; Huard, K.;* Altman, R. A.*
61. On the Metabolic Stability of Fluorinated Small Molecules: A Physical Organic Chemistry Perspective
Bhattarai, P. B.; Trombley, T. A.; Altman, R. A.*
44. Fluoroalkylation of Dextromethorphan Improves CNS Exposure and Metabolic Stability
Sorrentino, J. P.; Altman, R. A.*
43. Modulating β-Arrestin-2 Recruitment at the δ- and μ-Opioid Receptors
Sharma K. S.; Cassell, R. J.; Meqbil, Y. J.; Su, H.; Blaine, A. T.; Cummins, B. R.; Mores, K. L.; Johnson, D.; van Rijn, R. M.;* Altman, R. A.*
37. Late-Stage Conversion of a Metabolically Labile Aryl Methyl Ether-Containing Natural Product to Fluoroalkyl Analogues
Sorrentino, J. S.; Ambler, B. R.; Altman, R. A.*
29. Synthesis of Leu-Enkephalin Peptidomimetics Containing Trifluromethylalkenes as Amide Isopolar Mimics
Eeda, V.; Selvaraju, M.; Altman, R. A.*
28. Tyr1-ψ[(Z)CF═CH]-Gly2 Fluorinated Peptidomimetic Improves Distribution and Metabolism Properties of Leu-Enkephalin
Altman, R. A.*; Sharma, K. K.; Rajewski, L. G.; Toren, P. C.; Baltezor, M. J.; Pal, M.; Karad, S. N.
24. Synthesis and Opioid Activity of Tyr1–ψ[(Z)CF=CH]–Gly2 and Tyr1–ψ[(S)/(R)-CF3CH–NH]–Gly2 Leu-enkephalin Fluorinated Peptidomimetics
Karad, S. N.; Pal, M.; Crowley, R. S.; Prisinzano, T. E.; Altman, R. A.*